An update to python-rrdtool was released today. Version 0.1.1 adds support for Python 2.x and fixes some minor issues that came up when porting the original Python binding for Python 3.
You can find more information at the project page on Github.
The installation of the module is pretty easy. All you need is to have rrdtool installed (and its headers) and of course the header files for your Python version.
Assuming you want to install it via pip, use
# pip install https://github.com/commx/python-rrdtool/tarball/master
You can also install it from sources by downloading the source and run
# python setup.py install
python-rrdtool is a Python binding for rrdtool. It works with both Python 2.x and 3.x and comes with an object-oriented interface as well.